Clinical Neurophysiology
Volume 112, Issue 9 , Pages 1761-1772 , September 2001

Cortical current density reconstruction of interictal epileptiform activity in temporal lobe epilepsy

  • H.-J. Huppertz

      Affiliations

    • Epilepsy Center, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • Department of Neurology, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49-761-270-5001; fax: +49-761-270-5003
    • ,
  • S. Hoegg

      Affiliations

    • Epilepsy Center, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • Department of Neurology, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • ,
  • C. Sick

      Affiliations

    • Department of Neurology, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • ,
  • C.H. Lücking

      Affiliations

    • Department of Neurology, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • ,
  • J. Zentner

      Affiliations

    • Department of Neurosurgery, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • ,
  • A. Schulze-Bonhage

      Affiliations

    • Epilepsy Center, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany
    • ,
  • R. Kristeva-Feige

      Affiliations

    • Department of Neurology, University of Freiburg, Breisacher Strasse 64, D-79106 Freiburg, Germany

,Accepted 4 May 2001.

References 

  1. Alarcon G, Guy CN, Binnie CD, Walker SR, Elwes RD, Polkey CE. Intracerebral propagation of interictal activity in partial epilepsy: implications for source localisation. J Neurol Neurosurg Psychiatry. 1994;57:435–449
  2. Assaf BA, Ebersole JS. Continuous source imaging of scalp ictal rhythms in temporal lobe epilepsy. Epilepsia. 1997;38(10):1114–1123
  3. Ball T, Schreiber A, Feige B, Wagner M, Lücking CH, Kristeva-Feige R. The role of higher-order motor areas in voluntary movement as revealed by high-resolution EEG and fMRI. Neuroimage. 1999;10:682–694
  4. Baumgartner C, Lindinger G, Ebner A, Aull S, Serles W, Olbrich A, et al. Propagation of interictal epileptic activity in temporal lobe epilepsy. Neurology. 1995;45(1):118–122
  5. Boon P, D'Have M, Adam C, Vonck K, Baulac M, Vandekerckhove T, et al. Dipole modeling in epilepsy surgery candidates. Epilepsia. 1997;38(2):208–218
  6. Boon P, D'Have M, Van Hoey G, Vanrumste B, Vonck K, Adam C, et al. Source localization in refractory partial epilepsy. Rev Neurol (Paris). 1999;155:499–508
  7. Buchner H, Waberski TD, Fuchs M, Wischmann HA, Wagner M, Drenckhahn R. Comparison of realistically shaped boundary-element and spherical head models in source localization of early somatosensory evoked potentials. Brain Topogr. 1995;8(2):137–143
  8. Chatrian GE, Bergamini L, Dondey M, Klass DW, Lennox-Buchtal M, Petersen I. A glossary of terms most commonly used by clinical electroencephalographers. Electroenceph clin Neurophysiol. 1974;37:538–548
  9. Cohen D, Cuffin BN. Demonstration of useful differences between magnetoencephalogram and electroencephalogram. Electroenceph clin Neurophysiol. 1983;56:38–51
  10. Cuffin BN. A comparison of moving dipole inverse solutions using EEGs and MEGs. IEEE Trans Biomed Eng. 1985;32:905–910
  11. Diekmann V, Becker W, Jürgens R, Grozinger B, Kleiser B, Richter HP, et al. Localisation of epileptic foci with electric, magnetic and combined electromagnetic models. Electroenceph clin Neurophysiol. 1998;106:297–313
  12. Ebersole JS. Non-invasive localization of the epileptogenic focus by EEG dipole modeling. Acta Neurol Scand. 1994;152:20–28
  13. Ebersole JS. EEG source modeling. The last word. J Clin Neurophysiol. 1999;16:297–302
  14. Engel J, Van Ness PC, Rasmussen TB, Ojemann LM. Outcome with respect to epileptic seizures. In:  Engel J editors. Surgical treatment of the epilepsies. New York, NY: Raven Press; 1993;p. 609–621
  15. Fuchs M, Wischmann HA, Wagner M, Theissen A. Performance of realistically shaped boundary element method volume conductor models. BIOMAG98 Abstracts, 1998;86.
  16. Fuchs M, Wagner M, Kohler T, Wischmann HA. Linear and nonlinear current density reconstructions. J Clin Neurophysiol. 1999;16:267–295
  17. Geddes LA, Baker LE. The specific resistance of biological material – a compendium of data for the biomedical engineer and physiologist. Med Biol Eng. 1967;5:271–293
  18. Gevins A, Brickett P, Costales B, Le J, Reutter B. Beyond topographic mapping: towards functional-anatomical imaging with 124-channel EEGs and 3-D MRIs. Brain Topogr. 1990;3:53–64
  19. Gigli GL, Valente M. Sleep and EEG interictal epileptiform abnormalities in partial epilepsy. Clin Neurophysiol. 2000;111(Suppl 2):60–64
  20. Grave de Peralta Menendez R, Gonzalez Andino SL, Morand S, Michel CM, Landis T. Imaging the electrical activity of the brain: ELECTRA. Hum Brain Mapp. 2000;9(1):1–12
  21. Grimm C, Schreiber A, Kristeva-Feige R, Mergner T, Hennig J, Lücking CH. A comparison between electric source localisation and fMRI during somatosensory stimulation. Electroenceph clin Neurophysiol. 1998;106(1):22–29
  22. Hamalainen MS, Ilmoniemi RJ. Interpreting magnetic fields of the brain: minimum norm estimates. Med Biol Eng Comput. 1994;32(1):35–42
  23. Henderson CJ, Butler SR, Glass A. The localization of equivalent dipoles of EEG sources by the application of electrical field theory. Electroenceph clin Neurophysiol. 1975;39:117–130
  24. Huppertz HJ, Hof E, Klisch J, Wagner M, Lücking CH, Kristeva-Feige R. Localization of interictal delta and epileptiform EEG activity associated with focal epileptogenic brain lesions. Neuroimage. 2001;13(1):15–28
  25. Huppertz HJ, Otte M, Grimm C, Kristeva-Feige R, Mergner T, Lücking CH. Estimation of the accuracy of a surface matching technique for registration of EEG and MRI data. Electroenceph clin Neurophysiol. 1998;106:409–415
  26. Ilmoniemi RJ. Estimates of neuronal current distributions. Acta Otolaryngol Suppl Stockh. 1991;491:80–86
  27. Ilmoniemi RJ. Models of source currents in the brain. Brain Topogr. 1993;5(4):331–336
  28. Kobayashi K, Merlet I, Gotman J. Separation of spikes from background by independent component analysis with dipole modeling and comparison to intracranial recording. Clin Neurophysiol. 2001;112(3):405–413
  29. Kober H, Grummich P, Vieth J. Precise fusion of MEG and MRI tomography using a surface fit. Biomed Engineer (Berlin). 1993;38(Suppl):355–356
  30. Koles ZJ. Trends in EEG source localization. Electroenceph clin Neurophysiol. 1998;106:127–137
  31. Krings T, Chiappa KH, Cuffin BN, Buchbinder BR, Cosgrove GR. Accuracy of electroencephalographic dipole localization of epileptiform activities associated with focal brain lesions. Ann Neurol. 1998;44(1):76–86
  32. Krings T, Chiappa KH, Cuffin BN, Cochius JI, Connolly S, Cosgrove GR. Accuracy of EEG dipole source localization using implanted sources in the human brain. Clin Neurophysiol. 1999;110:106–114
  33. Kristeva-Feige R, Grimm C, Huppertz HJ, Otte M, Schreiber A, Jäger D, et al. Reproducibility and validity of electric source localisation with high-resolution electroencephalography. Electroenceph clin Neurophysiol. 1997;103(6):652–660
  34. Lantz G, Michel CM, Pascual-Marqui RD, Spinelli L, Seeck M, Seri S, et al. Extracranial localization of intracranial interictal epileptiform activity using LORETA (low resolution electromagnetic tomography). Electroenceph clin Neurophysiol. 1997;102:414–422
  35. Lopes da Silva F, Van Rotterdam A. Biophysical aspects of EEG and magnetoencephalogram generation. In:  Niedermeyer E,  Lopes da Silva F editor. Electroencephalography. Basic principles, clinical applications, and related fields. Baltimore, MD: Williams and Wilkins; 1993;p. 78–91
  36. Merlet I, Gotman J. Reliability of dipole models of epileptic spikes. Clin Neurophysiol. 1999;110:1013–1028
  37. Merlet I, Gotman J. Dipole modeling of scalp electroencephalogram epileptic discharges: correlation with intracerebral fields. Clin Neurophysiol. 2001;112(3):414–430
  38. Merlet I, Garcia-Larrea L, Gregoire MC, Lavenne F, Mauguiere F. Source propagation of interictal spikes in temporal lobe epilepsy. Correlations between spike dipole modelling and [18F]fluorodeoxyglucose PET data. Brain Pt 2. 1996;119:377–392
  39. Nakasato N, Levesque MF, Barth DS, Baumgartner C, Rogers RL, Sutherling WW. Comparisons of MEG, EEG, and ECoG source localization in neocortical partial epilepsy in humans. Electroenceph clin Neurophysiol. 1994;91(3):171–178
  40. Pacia SV, Ebersole JS. Intracranial EEG substrates of scalp ictal patterns from temporal lobe foci. Epilepsia. 1997;38(6):642–654
  41. Pascual-Marqui RD, Michel CM, Lehmann D. Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. Int J Psychophysiol. 1994;18(1):49–65
  42. Pelizzari CA, Chen GT, Spelbring DR, Weichselbaum RR, Chen CT. Accurate three-dimensional registration of CT, PET, and/or MR images of the brain. J Comput Assisted Tomogr. 1989;13:20–26
  43. Phillips JW, Leahy RM, Mosher JC. MEG-based imaging of focal neuronal current sources. IEEE Trans Med Imaging. 1997;16:338–348
  44. Robinson SE, Vrba J. Functional neuroimaging by synthetic aperture magnetometry. In:  Yoshimoto T,  Kotani M,  Karibe H,  Nakasato N editor. Recent advances in biomagnetism. Sendai: Tohoku University Press; 1999;p. 302–305
  45. Roth BJ, Balish M, Gorbach A, Sato S. How well does a three-sphere model predict positions of dipoles in a realistically shaped head?. Electroenceph clin Neurophysiol. 1993;87(4):175–184
  46. Roth BJ, Ko D, von Albertini-Carletti IR, Scaffidi D, Sato S. Dipole localization in patients with epilepsy using the realistically shaped head model. Electroenceph clin Neurophysiol. 1997;102(3):159–166
  47. Sammaritano M, Gigli GL, Gotman J. Interictal spiking during wakefulness and sleep and the localization of foci in temporal lobe epilepsy. Neurology. 1991;41:290–297
  48. Scherg M. Fundamentals of dipole source potential analysis. In:  Hoke M editors. Advances in audiology. Basel: Karger; 1990;p. 40–69
  49. Scherg M, Bast T, Berg P. Multiple source analysis of interictal spikes: goals, requirements, and clinical value. J Clin Neurophysiol. 1999;16:214–224
  50. Shindo K, Ikeda A, Musha T, Terada K, Fukuyama H, Taki W, et al. Clinical usefulness of the dipole tracing method for localizing interictal spikes in partial epilepsy. Epilepsia. 1998;39:371–379
  51. Sick C, Lücking CH, Wiesendanger M, Kristeva-Feige R. Comparison of different cortical current density methods for electric source reconstruction. Proceedings of the 30th Annual Meeting of the Society for Neuroscience, New Orleans, LA, Nov 4–9, 2000. p. 2203.
  52. Stefan H, Schüler P, Abraham-Fuchs K, Schneider S, Gebhardt M, Neubauer U, et al. Magnetic source localization and morphological changes in temporal lobe epilepsy: comparison of MEG/EEG, ECoG and volumetric MRI in presurgical evaluation of operated patients. Acta Neurol Scand. 1994;152(Suppl):83–88
  53. Uutela K, Hamalainen M, Somersalo E. Visualization of magnetoencephalographic data using minimum current estimates. Neuroimage. 1999;10:173–180
  54. Waberski TD, Buchner H, Lehnertz K, Hufnagel A, Fuchs M, Beckmann R, et al. Properties of advanced headmodelling and source reconstruction for the localization of epileptiform activity. Brain Topogr. 1998;10(4):283–290
  55. Waberski TD, Buchner H, Perkuhn M, Gobbele R, Wagner M, Kucker W, et al. N30 and the effect of explorative finger movements: a model of the contribution of the motor cortex to early somatosensory potentials. Clin Neurophysiol. 1999;110:1589–1600
  56. Waberski TD, Gobbele R, Herrendorf G, Steinhoff BJ, Kolle R, Fuchs M, et al. Source reconstruction of mesial–temporal epileptiform activity: comparison of inverse techniques. Epilepsia. 2000;41(12):1574–1583
  57. Wagner M. ekonstruktion neuronaler Ströme aus bioelektrischen und biomagnetischen Messungen auf der aus MR-Bildern segmentierten Hirnrinde (doctoral thesis). Aachen: Shaker Verlag; 1998;
  58. Wagner M, Fuchs M, Wischmann HA, Ottenberg K, Dösel O. Cortex segmentation from 3D MR images for MEG reconstructions. In:  Baumgartner C editors. Biomagnetism: fundamental research and clinical applications. Amsterdam: Elsevier Science (IOS Press); 1995;p. 433–438
  59. Wang JZ, Williamson SJ, Kaufman L. Magnetic source images determined by a lead-field analysis: the unique minimum-norm least-squares estimation. IEEE Trans Biomed Eng. 1992;39(7):665–675

PII: S1388-2457(01)00588-0

Clinical Neurophysiology
Volume 112, Issue 9 , Pages 1761-1772 , September 2001

Article Tools

* Image Usage & Resolution